Pharmacy benefit managers, the entities that process payments between drugstores and health benefit plans, are continuing their fight against an Arkansas law that they say will raise the cost of prescription medicine.

The appeal of a March 1 decision by Chief U.S. District Judge Brian S. Miller of Little Rock is the latest skirmish in a long-standing feud. Pharmacies accused PBMs of being unnecessary middlemen whose very existence has resulted in consumers paying more for prescription drugs. PBMs, on the other hand, describe themselves as champions of the consumer that negotiate better drug prices in exchange for a share of the savings.

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